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Understanding Fetal Bovine Serum (FBS): Composition, Applications, and Ethical Alternatives in Research
Fetal Bovine Serum (FBS) is one of the most widely used supplements in cell culture and biotechnology research. Derived from the blood of bovine fetuses, FBS provides essential nutrients, growth factors, and hormones that support the survival, proliferation, and function of cultured cells.
Due to its rich biological composition and ability to support a wide range of cell types, FBS has been a cornerstone of life science, pharmaceutical, and vaccine research for decades. However, as demand grows, ethical sourcing and the exploration of serum-free alternatives are becoming increasingly important.
What Is Fetal Bovine Serum (FBS)?
Fetal Bovine Serum is the liquid portion of clotted blood collected from bovine fetuses during the slaughter of pregnant cows. After collection, the serum is:
Centrifuged to remove blood cells and debris.